SANTA CLARA — When the 49ers opened the game, they featured three wide receivers with only Samuel was lined up in the backfield and he carried the ball on a traditional running play.
But the rest of the day belonged to Mason, who gained 123 yards on 24 carries and scored a touchdown.
Quarterback Brock Purdy managed to spread the ball to Samuel and George Kittle and Jauan Jennings for nearly all the 49ers offense with 175 yards and three touchdowns.
After the 49ers settled for a field goals on their first two possessions, Purdy got the 49ers into the end zone for a 20-0 lead with 3:18 remaining in the first half.
All-Pro linebacker Fred Warner supplied the 49ers with best defense early in the game when he made an interception of Patriots’ quarterback Jacoby Brissett’s pass, got to his feet and ran 45 yards into the end zone.
New England’s only touchdown came at the beginning of the second half after Isaac Guerendo fumbled the opening kickoff and the Patriots recovered the loose ball at the 27-yard line.
Brissett capped the five-play touchdown drive with a 5-yard touchdown pass to tight end Austin Hooper.
NEXT: The Patriots return home for the second game at Gillette Stadium while the 49ers stay home to face the Arizona Cardinals next Sunday, October 6, 1:05 pm at Levi’s stadium.
